Abstract
Parkinson’s disease is the second most prevalent neurodegenerative disease worldwide. Previous models of the disease solely focused on the effects happening in the brain, specifically the neurodegeneration of dopaminergic neurons which causes impairment in movement. Recent research has been shifting the focus to the gut microbiome since many patients with Parkinson’s Disease have gastrointestinal issues that can precede the diagnosis of Parkinson’s Disease by over a decade. It is unclear if Parkinson’s Disease starts in the gut or if gut issues are caused by the disease. Either way, the gut microbiome influences the progression and development of the disease since gut dysbiosis is found in most patients with Parkinson’s disease. This research proposal aims to address the link between the gut microbiome and Parkinson’s disease and the possibility of treating and preventing the disease through dietary and lifestyle modifications, such as exercise, and a possible study design to address the link between these factors and the development of Parkinson’s Disease.
How to Cite
Bassett, G., (2020) “Proposed Longitudinal Analysis of the Modulation of the Gut Microbiome Through Diet and Exercise for the Prevention and Treatment of Parkinson’s Disease”, Capstone, The UNC Asheville Journal of Undergraduate Scholarship 33(1).
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