Abstract
Due to the lack of novel antibiotic discovery since the 1980’s, the rapidly increasing number of antibiotic resistant bacteria has become a global health concern. Correlating with the misuse of antibiotics and the lack of funding for research, once treatable bacterial infections are now presenting with multi-drug resistance leading to more than 35,000 deaths a year in the United States alone. To slow the progression of multi-drug resistant bacteria, research in this field is being refunded and is focusing on developing new methods for antibiotic discoveries. Mining for natural products produced by microbes has regained popularity and advances in technology are proving to drastically reduce the rediscovery rate that once halted antibiotic research. Almost all antibiotics currently in use were mined from natural products, proving this method is extremely successful and has more to offer. Here an overview of the history of antibiotic resistance, priority pathogens, streamlined and new research techniques, and research of extracting a novel antibiotic from a Herbaspirillum species of bacteria that is capable of inhibiting both Staphylococcus aureus and Escherichia coli is discussed.
How to Cite
Ham, A. L., (2022) “Extraction, Isolation, and Characterization of a Novel Compound Presenting with Antibiotic Properties from Herbaspirillum sp.”, Capstone, The UNC Asheville Journal of Undergraduate Scholarship 35(1).
7
Views
2
Downloads